Vyepti cost 2025: Coupons, savings, and more guide

Hey there, friend. If you've landed on this page, you're probably wondering exactly how much Vyepti will set you back and whether there's any way to soften the blow. Let's skip the fluff and get straight to the facts you need the price, the insurance tricks, the coupons, and a few reallife stories that will make the numbers feel a lot less abstract.

Quick Bottom Line

List price (WAC) for a 100mg vial in 2025 is roughly $1,888$1,980. Most patients, however, don't pay that full amount. With commercial insurance paired with the VyeptiCONNECT copay program, outofpocket can drop to under $200, sometimes even $0. Medicare users typically see a 20% coinsurance (about $380) plus an infusion fee, while anyone without coverage can expect to pay the full list price unless they grab a discount card or qualify for a patientassistance program.

Bottom line: the sticker price is high, but the actual amount you reach for your wallet can be dramatically lower if you know where to look.

Price Fundamentals

What is the "list price" or "wholesale acquisition cost (WAC)"?

The list price, often called the wholesale acquisition cost, is the price set by the manufacturer before any discounts, insurance negotiations, or rebates. Think of it as the "cover price" you'd see on a bookuseful for reference, but rarely the amount you actually pay.

Why does my bill differ from the list price?

Insurance contracts, pharmacy benefit managers, and infusioncenter negotiations all reshape the final charge. Your plan might cover a portion, or you might qualify for a copayassistance program that takes the drug cost off the table. Add in administration fees (the cost of the infusion chair, nursing time, and facility overhead) and the total you see on your statement can swing widely.

Example pricebreakdown

Scenario	List price (WAC)	Insurance type	Estimated outofpocket*
Commercial+VyeptiCONNECT	$1,888	Commercial	$0$200 (admin fee covered)
MedicarePartB	$1,888	Medicare	$380+infusion fee
No insurance	$1,888		$1,888+infusion fee
Discountcard (cash pay)	$1,888	Cash pay	$300$500 (depends on pharmacy)

*Numbers are illustrative; actual costs vary by state, provider, and specific plan.

Insurance Pathways

Commercial insurance

If you have an employerbased plan or bought coverage on the marketplace, you're in luck because you can tap into the VyeptiCONNECT program. This assistance covers the drug cost entirely and may also subsidize up to $200 of the infusion center's admin fee.

How to enroll in VyeptiCONNECT

1. Confirm your coverage is commercial (not Medicare or Medicaid).
2. Ask your prescribing neurologist to submit the VyeptiCONNECT enrollment form.
3. Wait 12weeks for approval and receive a copay card.
4. Present the card at every infusion appointment.

Medicare (PartB, Advantage, and supplemental plans)

Medicare typically pays 80% of the drug's cost after you meet the annual deductible, leaving you with a 20% coinsurance. Unfortunately, VyeptiCONNECT is not available to Medicare beneficiaries, but you can still look for specialtypharmacy mailorder programs that bundle the infusion fee into a single charge.

Sample Medicare cost calculator

Medicare type	Deductible met?	Coinsurance (20%)	Avg. infusion admin fee	Estimated total per infusion
PartB only	Yes	$378	$150$250	$528$628
Advantage w/ drug coverage	Yes	$0$150 (planspecific)	$100$200	$200$350

Medicaid & other government programs

Some state Medicaid plans cover Vyepti with little to no cost to the patient, but there are notable exceptions Massachusetts and Rhode Island, for instance, are not part of the VyeptiCONNECT assistance pool. The best move is to check your state's drug formulary or call your Medicaid office directly.

How to verify state coverage

Visit each state's Medicaid website (e.g., Massachusetts, Rhode Island) and search for "Vyepti." If it appears on the formulary, note any priorauthorization steps.

No insurance / underinsured

When insurance isn't an option, a good oldfashioned discount card can be a lifesaver. The Drugs.com discount card often knocks 3080% off the cash price, turning a near$2,000 bill into something more manageable.

Patient Assistance Program (PAP)

Lundbeck, the maker of Vyepti, runs a PAP for patients whose household income is below 400% of the federal poverty level. The application is a short questionnaire, and approved patients may receive the drug for as low as $0$100 per infusion.

Savings Tools

VyeptiCONNECT copay assistance

This is the flagship program for commercially insured patients. After enrollment, you'll receive a card that eliminates the drug cost and may cover up to $200 of the infusion center's fee. Remember: it's not available for Medicare or Medicaid beneficiaries.

Drugs.com discount card

Fast, free, and no insurance required. Print or download the card, show it at the pharmacy, and the system applies the discount automatically. It's especially handy for cashpay patients or when your insurance denies coverage.

Other thirdparty coupons

Programs like Optum Perks or pharmacyspecific savings (CVS, Walgreens) often provide a onetime discount of 1050% off the drug price. The catch? You can't stack these with insurance copays, so pick the option that gives you the lowest total outofpocket.

Comparison matrix

Program	Insurance required?	Max savings per infusion	Application time	Notes
VyeptiCONNECT	Commercial only	$0$200 admin + drug	12weeks	Not for Medicare/Medicaid
Drugs.com card	None (cash pay)	Up to 80% off	Instant	Must present at pharmacy
Optum Perks	Any (cannot combine)	Up to 50% off	Instant	Singleuse per prescription

RealWorld Stories

Case1 Beth, commercial insurance

Beth works at a tech firm with a solid PPO. She was diagnosed with chronic migraine and her neurologist prescribed Vyepti. After a quick call to the clinic, Beth's doctor submitted the VyeptiCONNECT form. Within ten days, Beth received a green card, walked into the infusion center, and paid $0 for her first dose. "I felt like I'd hit the jackpot," she laughed, "and the admin fee was waived too!"

Case2 John, Medicare beneficiary

John, 68, lives in Florida and relies on Medicare PartB. He paid roughly $380 in coinsurance plus a $180 infusion fee each quarter. When his pharmacist suggested a 90day mailorder program, John switched to a specialty pharmacy that bundled the infusion fee, shaving $45 off each visit. "It's not free, but the little savings add up," he noted.

Case3 Maria, uninsured

Maria lost her job and had no insurance when she needed Vyepti. She printed a Drugs.com discount card, presented it at the local infusion center, and the staff applied a 78% discount. Maria's outofpocket dropped from $1,950 to $430. "I was terrified about the cost," she admitted, "but the discount card felt like a lifeline."

Key takeaways

• Commercial patients often pay $0$200 when they enroll in VyeptiCONNECT.
• Medicare users can lower total costs by using specialtypharmacy mailorder options.
• Cashpay patients should explore discount cards and PAPs for the biggest savings.
• Realworld experiences show that a few minutes of paperwork can translate into hundreds of dollars saved.

StepbyStep Savings

1. Identify your insurance type. Look at your ID card or log into your portal to see if you're commercial, Medicare, Medicaid, or uninsured.
2. Visit the VyeptiCONNECT portal. If you have commercial coverage, fill out the short eligibility questionnaire.
3. Ask your prescriber. Request that they submit the enrollment form or, if you're uninsured, ask for a prescription you can take to a pharmacy that accepts discount cards.
4. Print or download a discount card. The Drugs.com card is free and works instantly for cashpay patients.
5. Call the infusion center. Confirm they accept your chosen savings program and ask about any additional admin fees.
6. Keep records. Save approval letters, receipts, and any correspondence. If a billing error pops up, you'll have the paperwork ready.

Following these steps usually saves you somewhere between $300 and $1,500 per year, depending on your situation.

Helpful Resources

When you're navigating the maze of drug pricing, reliable resources are priceless. Here are a few you'll want to bookmark:

• VyeptiCONNECT enrollment page the official home for the copayassistance program.
• Lundbeck's Patient Assistance Program call8772889125 for eligibility details.
• Drugs.com discount card instant cashpay savings.
• NeedyMeds & Medicine Assistance Tool great for locating additional charity programs.
• Ask a nurse or pharmacist directly. The dedicated Vyepti hotline (8334893784) can walk you through priorauthorization, enrollment, and any hidden fees.

Conclusion

Understanding Vyepti cost isn't just about staring at a big number on a bill; it's about knowing the levers you can pull to bring that number down. Whether you have commercial insurance and can use VyeptiCONNECT, rely on Medicare and explore specialtypharmacy options, or are cashpaying and need a discount card, the path to savings is there you just have to take the first step.

Take a moment now: check your insurance, grab a discount card, or call your doctor's office about the copay program. And if you've already gone through the process, we'd love to hear how it went. Drop a comment, share your tip, or ask a question we're all in this together, and your story could be the next lifeline for someone else.

Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult with a healthcare professional before starting any new treatment regimen.