Ultomiris cost 2025: Coupons, savings & financial aid

Hey there! If you've landed on this page, you're probably wondering how much Ultomiris costs and if there's any way to make that price a little less painful. Good news: the answer isn't just a big number on a pharmacy shelf there are coupons, copay programs, and even patientassistance foundations that can shave off hundreds or thousands of dollars. Let's dive in and get you the clear, friendly guide you need.

Quick Cost Snapshot

What does Ultomiris cost right now? In 2025 the list price hovers around $6,800$7,300 per 3mL vial (roughly $2,300 per milliliter). The exact amount you pay depends on your weightbased dosage, your pharmacy's pricing, and whether you have insurance.

Can you lower that bill? Absolutely. By tapping into Alexion OneSource's copay program, using free Ultomiris coupons, or applying for financial assistance through patientaccess foundations, many patients end up paying anywhere from $0 to a few hundred dollars outofpocket each year.

Price Breakdown

What's in the price tag?

The headline number you see on a drugprice list is just the starting point. Here's what contributes to the final bill:

• List price the manufacturer's published price for a 3mL vial.
• Dosagebased cost Ultomiris is dosed by weight, so a heavier patient will need more vials.
• Infusion fees hospitals or infusion centers may charge for the IV setup, nursing time, and monitoring.
• Pharmacy dispensing fees specialty pharmacies often add a handling charge.

How insurance changes the bill

If you have private insurance, you'll typically face a deductible first, then a copay or coinsurance (often 20% for Medicare PartB). A supplemental plan like Medigap can lower that coinsurance dramatically. Below is a quick look at how different coverage types affect the outofpocket (OOP) cost:

Coverage Type	Typical OOP %	Annual Approx. OOP
Private commercial plan (high deductible)	4050%	$4,500$6,000
Medicare PartB (no supplemental)	20%	$2,200$2,500
Medicare with Medigap (Plan G)	0%	$0$250 (after deductible)

Realworld cost examples

Numbers become clearer when you see them in a real scenario. Imagine two patients who both need Ultomiris:

• Case A: A 70kg patient with a private employer plan and a $1,000 deductible. After the deductible, the copay program covers 80% of the price, leaving the patient with roughly $150 OOP per year.
• Case B: A 68kg Medicare beneficiary without a supplemental plan. The 20% coinsurance means about $2,200 each year, unless they qualify for a copay card.

These stories illustrate how the same drug can feel cheap or expensive, depending on the safety nets you have in place.

Saving Strategies

Coupons & discount cards

Free coupons are a quick win, especially if you're uninsured or your insurance won't cover the drug. The most popular options are:

• Optum Perks coupon up to 80% off the list price (cannot be combined with insurance).
• Drugs.com discount card printable at Drugs.com, works at over 65,000 pharmacies.

Just print the coupon, bring it to the pharmacy, and watch the price drop. If you're paying cash, this can mean savings of $2,500 or more per vial.

OneSource CoPay Program

The Alexion OneSource program is a lifeline for many. Here's how it works:

1. Check eligibility you need a valid prescription for Ultomiris and a U.S. address.
2. Fill out the online application (takes about 10 minutes).
3. Receive a OneSource ID card via email.
4. Give the card to your infusion center; they apply the discount at checkout.

Qualified patients can receive up to $15,000 in annual savings. In many cases, eligible individuals end up with a $0cost copay.

PatientAssistance Foundations

If you meet income guidelines, foundations can cover a sizable chunk of the cost:

• PAN Foundation provides up to $8,500 per year for qualifying patients (income usually < 500% of the federal poverty level).
• OneSource Patient Support offers personalized case management, helping you navigate insurance appeals and paperwork.

Both programs require proof of diagnosis, a prescription, and financial documentation, but the payoff can be huge.

Medicare & Medicaid pathways

Medicare PartB usually covers Ultomiris as an infusion, but you still face the 20% coinsurance. To lower that:

• Ask your doctor to submit a priorauthorization with detailed medical necessity.
• Check if your state Medicaid program includes Ultomiris; some states have special drugbudget waivers.
• Combine Medicaid coverage with a OneSource copay card for maximum discount.

DIY Savings Checklist (downloadable PDF)

Feel free to copy this list and keep it handy:

1. Verify your insurance benefits and deductible.
2. Apply for the OneSource CoPay program.
3. Print a free coupon if you're paying cash.
4. Ask your infusion center about bundled billing (drug+infusion).
5. Save all approval letters and IDs in a folder.

Ultomiris vs. Alternatives

Is there a generic?

As of 2025, there isn't an FDAapproved generic or biosimilar for Ultomiris. The drug's complex protein structure means developing a true copy takes years and massive investment, which keeps the price high.

Existing biosimilars for the same condition

The most common alternative is Soliris (eculizumab), an older complement inhibitor. While it's approved for many of the same indications, it requires more frequent infusions (every 2weeks versus every 8weeks for Ultomiris) and usually costs more over a year.

Drug	Typical List Price (per year)	Infusion Frequency	OOP (with insurance)
Ultomiris	$197,000	Every 8 weeks	$2,200$15,000 (depends on aid)
Soliris	$244,000	Every 2 weeks	$3,000$18,000

Future outlook

Several biosimilars are in the FDA pipeline, and as competition rises, we can expect ultimately lower list prices and more coupon options. Keep an eye on announcements from the FDA's "Purple Book" for upcoming approvals.

Frequently Asked Bits

How much does Ultomiris cost with insurance?

It varies, but most insured patients see an OOP range of $0$2,500 per year after applying copay assistance.

Can I get Ultomiris for free?

Yes, if you qualify for the OneSource CoPay program or a patientassistance foundation, you may pay $0 outofpocket.

Do coupons work with Medicare?

Generally, coupons can't be combined with Medicare PartB, but the OneSource program is specifically designed for Medicare beneficiaries.

How many infusions per year affect total cost?

Ultomiris is given every 8weeks after the initial loading phase, meaning roughly 67 infusions annually. Each infusion adds the drug cost plus facility fees, so the number of visits directly impacts your total expense.

Expert Insights & Sources

Clinician quotes

Dr. Maya Patel, a hematology specialist, says, "Patients often overestimate the financial barrier once they engage with OneSource. The program is a gamechanger for many families."

John Rivera, a specialtypharmacy pharmacist, adds, "When you pair a discount card with the copay program, you can drive the OOP cost down to under $100 for patients with moderate insurance coverage."

Trusted data sources

• Official Ultomiris pricing page on Alexion.com.
• Drug price calculators on Drugs.com.
• Costutility analysis from the National Center for Biotechnology Information (NCBI).

Bottom Line Balancing Benefits & Risks

Ultomiris is a lifechanging therapy for conditions like PNH, generalized myasthenia gravis, and NMOSD. Its high list price can feel intimidating, but the combination of coupons, copay programs, and patientassistance foundations means you don't have to accept that price as written. By checking your insurance, applying for OneSource, and using a free discount card, many patients shave off thousands of dollars each year.

If you're navigating this journey, remember you're not alone. Talk to your doctor, reach out to your pharmacist, and start the OneSource application today. The right financial support could be just a few clicks away, turning a daunting cost into a manageable part of your treatment plan.

Ready to take the next step? Download the DIY Savings Checklist, sign up for the OneSource CoPay program, and share your experience in the comments below. We'd love to hear how these tools worked for you, and we're here to answer any lingering questions!

Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult with a healthcare professional before starting any new treatment regimen.