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FAQs
What causes the broad O-H stretch in the spectrum?
The broad 2500-3300 cm-1 O-H stretch results from intermolecular hydrogen bonding between ibuprofen molecules.
Where are aromatic C=C vibrations observed?
Aromatic C=C bending causes absorption around 1600 cm-1 in the ibuprofen IR spectrum.
How can IR detect ibuprofen degradation?
Changes in peak positions and intensities indicate degradation via oxidation, hydrolysis, or photochemical decomposition.
What shifts reveal ibuprofen binding interactions?
Binding to proteins or cyclodextrin causes shifts in the characteristic IR absorption band frequencies.
Can IR quantify ibuprofen in pharmaceuticals?
Yes, peak heights at 1708, 1154, and 1249 cm-1 allow accurate determinations of ibuprofen concentration.
Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult with a healthcare professional before starting any new treatment regimen.
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