Conventional Crohn's Disease Treatment Options

Understanding Crohn's Disease

Crohn's disease is an inflammatory bowel disease that causes inflammation and irritation in the digestive tract. It can lead to abdominal pain, severe diarrhea, fatigue, weight loss and malnutrition. While there is no known cure yet, several conventional treatment options can help reduce symptoms.

Anti-Inflammatory Medications

Corticosteroids like prednisone and budesonide are often first-line treatments for reducing inflammation caused by Crohn's flares. Though effective, long-term use can have significant side effects so they are not recommended for maintenance.

Immune System Suppressors

Medications like azathioprine, mercaptopurine, and methotrexate suppress the immune system response causing inflammation. They allow corticosteroid doses to be lowered and can keep Crohn's in remission when used long-term.

Biologic Therapies

Biologic agents like infliximab, adalimumab, certolizumab and others bind to proteins to block inflammation-triggering immune responses. Used long-term, they maintain remission in many patients.

Comparing Medication Delivery Methods

Crohn's medications come in various forms, each with their own uses, benefits and downsides to consider with your doctor:

Oral Tablets

Tablets like corticosteroids and immune system suppressors are taken by mouth. They travel through the digestive system, so absorption can be impacted by Crohns inflammation.

Injections

Self-injectable biologics allow patients to administer treatment at home. Timing and dosage can be personalized but the injections can be unpleasant for some.

Infusions

Intravenous infusion biologics are delivered through a vein in a medical facility. This allows larger, consistent doses but requires regular visits and IV access.

Individualizing Your Treatment Plan

There are many factors physicians consider when developing a Crohns treatment plan:

Location and Severity

Location of inflammation in the GI tract and severity of symptoms help determine which meds may work best and whether surgery could help.

Response to Treatment

If a medication successfully induces and maintains remission, continuing it long-term may be beneficial. Lack of response may necessitate trying another option.

Quality of Life Impact

Treatment goals involve both managing physical Crohns symptoms and improving overall health and quality of life on an ongoing basis.

Patient Preferences

Factors like out-of-pocket costs, convenience, self-injection preferences and more also play a role in selecting Crohns medications.

Open communication with your doctor allows customization of conventional therapy to meet your individual needs. While battling Crohns presents challenges, long-term remission is an achievable goal.

Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult with a healthcare professional before starting any new treatment regimen.