What is Berberine?
Berberine is a compound extracted from certain plants that has been used in traditional Chinese and Ayurvedic medicine for centuries. More recently, berberine has become popular as a health supplement due to emerging research on its wide range of potential benefits.
Where Does Berberine Come From?
Berberine is found in the stems, roots and bark of several different plants including:
- Barberry
- Goldenseal
- Goldthread
- Oregon grape
- Phellodendron
- Tree turmeric
The berberine is extracted and purified from these plants to create standardized capsules, tablets, powders and other berberine containing products.
Evidence-Based Health Benefits of Berberine
Here are some of the top science-backed ways berberine may benefit health:
1. Aids Blood Sugar Control
A number of studies have found berberine helps lower blood sugar and enhance the effectiveness of insulin. This makes it useful for managing type 2 diabetes and metabolic syndrome.
2. Lowers Cholesterol
By reducing cholesterol absorption, berberine can help lower LDL "bad" cholesterol and total cholesterol. The effects may be comparable to cholesterol-lowering statin drugs.
3. Reduces Blood Pressure
Research indicates berberine Relaxes blood vessels causing blood pressure levels to drop. This makes it helpful for hypertension.
4. Promotes Heart Health
The combination of improved cholesterol, blood pressure and blood sugar from berberine benefits heart health and reduces risk of heart disease.
5. Aids Weight Loss
Some research found berberine may help induce fat loss by increasing insulin sensitivity, regulating blood sugar levels and altering fat cell metabolism. Berberine also limits formation of new fat cells in the body.
6. Contains Antioxidants
Antioxidants in berberine help fight cellular damage from free radicals. This protects against oxidative stress and many associated diseases.
7. Has Anti-Inflammatory Effects
The compound demonstrates anti-inflammatory abilities which reduce swelling, fight infections, and decrease risk of developing chronic disease.
8. May Help Fight Cancer
Early test tube studies found berberine may hinder growth and spread of various cancer cells. More research is needed to confirm effects in humans.
Berberine for Weight Loss Reviews
Obesity continues to be a major health epidemic. Many are turning to berberine supplements as a potential natural weight loss solution given promising fat reducing effects shown in a some studies.
How Berberine Aids Fat Loss
Researchers believe berberine helps support weight loss through several mechanisms including:
- Increasing insulin sensitivity
- Balancing blood sugar levels
- Boosting metabolism
- Limiting formation of new fat cells
- Altering genes involved in processing fat
- Increasing beneficial gut bacteria
- Reducing intestinal absorption of fat
Berberine Weight Loss Clinical Studies
Most current research showing berberine for fat loss is limited to animal research. However, a few small human studies have produced promising results:
- Overweight adults taking 500 mg berberine 3 times daily for 12 weeks lost an average of 5 pounds vs. the placebo group. Body fat mass also decreased compared to placebo.
- Obese individuals who took 500 mg berberine 3 times per day for 3 months experienced significant decreases in body weight, BMI, waist circumference, and belly fat vs control group.
- People with metabolic syndrome taking 300-900 mg berberine daily for 3 months had greater body fat reduction compared to the placebo group.
Larger scale, longer term human trials are still needed. But the early evidence indicates berberine supplementation can aid healthy weight loss, especially around the abdominal area.
Berberine Dosage for Weight Loss
Most studies showing berberine helps promote fat loss through enhanced metabolism used doses between 300-900 mg taken 2-3 times daily. It's best to start low at 300 mg once or twice per day and gradually increase based on tolerance.
Berberine Weight Loss Reviews
Here’s what some people taking berberine supplements reported regarding its effectiveness for losing weight from belly fat, love handles, thighs etc based on reviews:
- “I lost about 15 stubborn pounds around my stomach taking berberine. My pants are looser than they’ve been in years.”
- “Been taking berberine for 2 months and its been amazing for dropping fat while I’m in a calorie deficit and lifting weights. Belly pooch is disappearing.”
- “I've struggled trying to slim my thighs and rear. The scale didn't move much but I lost a couple inches of fat taking this.”
As with any supplement, berberine works best paired with a healthy diet and active lifestyle for optimum fat burning effects. But it can provide that extra metabolic boost to move the needle.
Is Berberine Safe?
Berberine is generally well tolerated by most healthy adults when used short term (up to 3 months). Potential minor side effects can include:
- GI upset like diarrhea, cramping, flatulence
- Constipation
- Nausea
Starting with smaller doses around 300 mg once daily can help minimize risk of stomach issues. It’s also best avoided in pregnant/nursing women due to lack of safety research.
Berberine should also not be taken long-term or in certain higher risk groups without medical guidance. This includes people with kidney disease, liver disease, heart disease or diabetes due to risks like low blood sugar.
Talk to your doctor before taking berberine if you take any medications as major interactions are possible. Stop taking at least 2 weeks before any scheduled surgeries.
When taken appropriately by healthy adults in moderate doses for short periods, berberine is well tolerated with a relatively low risk of adverse effects.
Should You Try Berberine?
As more preliminary research uncovers berberine's many health promoting properties, it shows promising potential. Supplementing with berberine can provide natural benefits for:
- Enhancing blood sugar control
- Improving cholesterol levels
- Lowering elevated blood pressure
- Aiding weight loss efforts
However, always talk to your physician before starting any new herb or supplement, especially if you take any medications or have underlying health conditions.
For healthy individuals, taking 300-900 mg high quality berberine per day in divided doses for up to 12 weeks appears reasonably safe based on current evidence. Just be sure to ease into supplementation slowly and take precautions to avoid side effects.
By boosting metabolism, balancing blood sugar hormones, altering fat processing genes and other means, adding berberine to a healthy regimen shows promise if you’re looking to trim down.
FAQs
How much berberine should I take daily?
Most studies showing berberine's weight loss benefits used doses between 300-900 mg daily, split into 2 or 3 doses. Start with 300 mg once a day and gradually increase based on your tolerance.
When is the best time to take berberine?
Berberine is best taken before meals, especially before your largest meals when blood sugar and insulin spikes tend to be highest. Spacing smaller doses 2-3 times throughout the day maximizes effects.
How long does berberine take to work?
It can take 2-3 months of consistent berberine supplementation for notable results in weight loss, blood sugar control, cholesterol improvement etc. Patience and persistence is key.
Can I take berberine long-term?
Berberine use beyond 3 months is not generally recommended, especially without medical supervision. Cycling on and off berberine every few months allows your body to re-sensitize to its effects for maximum results.
Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult with a healthcare professional before starting any new treatment regimen.
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