Pictures of Multiple Myeloma Rash and Skin Conditions

Pictures of Multiple Myeloma Rash and Skin Conditions
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Recognizing Multiple Myeloma Rash and Other Skin Conditions

Multiple myeloma is a type of blood cancer that forms in plasma cells found in bone marrow. It can cause a variety of symptoms, including bone pain, fatigue, and susceptibility to infections.

Skin conditions are also common with multiple myeloma. Patients may develop rashes, lesions, bruising, or other problems. Being able to recognize the signs of a multiple myeloma rash can help guide proper treatment.

In this article, well look at pictures of multiple myeloma rash and discuss the causes, symptoms, diagnosis, and treatment for various myeloma-related skin conditions.

Why Rashes Develop

There are several reasons why multiple myeloma often leads to skin rashes or other problems:

  • Reduced immune function makes patients prone to infections that affect the skin.
  • Kidney damage from myeloma causes waste buildup and electrolyte imbalances.
  • Abnormal plasma cells interfere with normal antibody production.
  • Chemotherapy drugs may cause allergic reactions or skin toxicity.

Some of the most common multiple myeloma rashes and skin conditions include:

Shingles Rash

Shingles is a viral infection that causes a painful rash of fluid-filled blisters. Its caused by the varicella-zoster virus, the same virus that causes chickenpox.

Multiple myeloma patients are at high risk for shingles due to a weakened immune system. Symptoms include burning, tingling pain and blisters along nerve pathways.

Shingles rash picture

Antiviral medications like acyclovir can treat shingles. Prompt treatment helps reduce the risk of complications like persistent nerve pain.

Bacterial Skin Infections

Bacterial infections of the skin are also more likely in myeloma patients. Two types include:

Cellulitis

Cellulitis causes red, swollen, tender skin that spreads rapidly. Common locations include the legs, arms, and face. It requires antibiotic treatment.

Picture of cellulitis skin infection rash

Folliculitis

Folliculitis results from infection and inflammation of the hair follicles. It develops as crops of small, itchy, pus-filled bumps.

Folliculitis rash picture

Good hygiene and topical antibiotics usually clear up mild folliculitis. More severe cases may require oral antibiotics.

Candidiasis Fungal Infections

Candida fungus commonly causes skin infections in cancer patients. Areas typically affected include:

  • Oral thrush - white patches or red soreness in the mouth
  • Vaginal yeast infection - vaginal itching and discharge
  • Skin yeast infection - a red, scaly, itchy rash

Antifungal medications effectively treat candida overgrowth. Practice good oral hygiene and avoid douching to help prevent infections.

Picture of oral thrush

Multiple Myeloma Rash from Chemotherapy

Chemotherapy drugs used to treat multiple myeloma often cause skin reactions as a side effect. These include:

Hand-Foot Syndrome

Hand-foot syndrome causes redness, swelling, numbness, and tingling on the palms and soles. Small blisters may form and peel.

Picture of hand-foot syndrome rash

Maculopapular Rash

This is an allergic reaction marked by flat, red bumps over the body. Its often itchy and may occur alongside hives or facial swelling.

Maculopapular rash photo

Topical steroids, antihistamines, and adjusting medications can help manage chemotherapy-related rashes.

Paraproteinemic Vasculitis Rash

About 10% of myeloma patients develop paraproteinemic vasculitis, an inflammation of the small blood vessels. Symptoms include:

  • Tiny red-purple spots called purpura
  • Bruise-like rashes called palpable purpura
  • Reddish-brown skin nodules
  • Painful leg ulcers
Paraproteinemic vasculitis rash photo

Steroids, plasma exchange, immunosuppressants, and treating the myeloma can help manage vasculitis.

Aquagenic Pruritus

Aquagenic pruritus causes severe itching and a burning sensation after contact with water. Tiny red bumps may appear on the skin.

Its due to abnormal immunoglobulin proteins produced by myeloma plasma cells that bind to water. Avoiding water exposure and controlling myeloma helps provide relief.

Diagnosing Multiple Myeloma Skin Conditions

See your doctor promptly if you develop any new, concerning skin rashes or problems. Early diagnosis and treatment improves outcomes.

Your doctor will examine the rash and consider your full medical history. Tests may include:

  • Blood tests to check for infecting pathogens
  • Biopsy of skin lesions
  • Bone marrow biopsy to assess myeloma

Identifying whether the rash is due to an infection, drug reaction, or vasculitis will inform proper treatment.

Treatment for Multiple Myeloma Rash

Treatment depends on the underlying cause but may include:

  • Antibiotics for bacterial infections
  • Antifungals for fungal infections
  • Antiviral medication for shingles
  • Topical steroids for inflammation and itching
  • Antihistamines for allergic reactions
  • Adjusting medications if its a drug rash
  • Steroids, immunosuppressants, or plasma exchange for vasculitis
  • Radiation, chemotherapy, or stem cell transplant to treat myeloma

Good skin care and hygiene practices can help prevent infections that lead to rashes. Moisturizing creams relieve chemotherapy-related skin dryness and irritation.

The Takeaway

Rashes and skin conditions are common issues faced by those with multiple myeloma. Being able to identify characteristics of the rash assists with prompt diagnosis and management.

Seeking treatment right away for any new skin problems is important to alleviate symptoms and prevent complications. With proper treatment, most myeloma-related skin rashes can be effectively managed.

FAQs

What causes rashes in multiple myeloma patients?

Rashes may be caused by infections, chemotherapy side effects, paraproteinemic vasculitis, or buildup of abnormal proteins.

What does a multiple myeloma rash look like?

Myeloma rashes can look like shingles, cellulitis, folliculitis, thrush, hand-foot syndrome, purpura, or generalized red bumps.

Is rash a common symptom of multiple myeloma?

Yes, over 50% of multiple myeloma patients develop rashes and other skin conditions related to their cancer.

How are multiple myeloma skin rashes diagnosed?

Doctors examine the rash and may run tests like bloodwork, skin biopsy, or bone marrow biopsy to diagnose the cause.

How are rashes treated in multiple myeloma patients?

Treatment depends on the cause but may include antibiotics, antivirals, antifungals, antihistamines, steroids, or chemotherapy for the myeloma.

Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult with a healthcare professional before starting any new treatment regimen.

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