Understanding Arctiva: The Novel Eczema Cream
People struggling with chronic, treatment-resistant eczema finally have new hope. In 2021, the FDA approved Arctiva cream - the first topical JAK inhibitor medication for managing moderate to severe atopic dermatitis flare-ups in adults and children ages 12 and up.
How Arctiva Eczema Cream Works
Arctiva contains the active drug ruxolitinib, which functions as a Janus kinase (JAK) inhibitor. JAK enzymes mediate inflammatory responses in the body that drive eczema flare ups and skin damage.
By blocking these JAK signals, Arctiva essentially dampens the body’s destructive overreaction to external irritants that characterize atopic dermatitis flares. This addresses eczema at its roots rather than just masking visible skin symptoms.
Benefits of Arctiva for Eczema Treatment
Traditional eczema medications like topical corticosteroids and systemic immunosuppressants come with concerning side effects that limit long-term use. Many also become less effective over time.
As a non-steroidal option, Arctiva avoids risks like skin atrophy and adrenal gland suppression from steroids. It can be applied safely twice a day for up to six weeks straight. Patients switching from ineffective steroids often find their eczema newly responsive to Arctiva’s different mechanism of action against flare factors.
Arctiva Clinical Trial Results
The referenced article reports Phase 3 clinical trials demonstrated Arctiva’s superior efficacy over placebo. After two weeks, over half treated with Arctiva achieved clear or almost clear skin, compared to only 15 percent receiving placebo.
Many trial patients experienced significant itch relief within a day or two of first Arctiva application. Continued daily use prevented flare recurrence more successfully than placebo as well.
These robust research results led the FDA to approve Arctiva (ruxolitinib) cream as a novel anti-inflammatory addition to our eczema treatment arsenal.
Using Arctiva Cream Correctly and Safely
Arctiva offers fresh hope for frustrating eczema symptoms. But like any medication, users must follow proper protocols to ensure safe, effective application.
Understanding Arctiva Side Effects
Clinical trials found Arctiva cream largely well-tolerated without significant safety issues. Mild application site reactions like temporary burning, stinging or redness commonly resolve within a day.
Rarely, introducing powerful new drugs can trigger new allergies or reactions in sensitive individuals. Discontinue Arctiva use if any concerning symptoms develop like severe rash, swollen lymph nodes or difficulty breathing.
Arctiva Dosage Instructions
Apply a thin layer of Arctiva cream to affected areas of eczema twice daily. Rub it in gently until fully absorbed into the skin without leaving any visible residue behind.
Wash hands thoroughly after application to avoid inadvertently transferring any cream to eyes, mouth or other mucus membranes. Be extremely careful to keep Arctiva away from open cuts or wounds.
Treatment duration depends on severity of eczema at baseline. Continue applying Arctiva for as many weeks as prescribed by your dermatologist based on your flares.
Who Should Avoid Using Arctiva
Arctiva has not been evaluated in pregnant or breastfeeding women, so they should opt for other eczema treatments until more safety data emerges.
Immunosuppressed patients like those on biologics for conditions such as rheumatoid arthritis or inflammatory bowel disease also cannot use Arctiva due to infection risk.
Finally, anyone with an allergy or sensitivity to Arctiva’s ingredients should avoid this topical cream given risk of further reactions.
Maximizing Arctiva's Eczema Relief Potential
While Arctiva can significantly calm flare factors like inflammation and itching, adjunctive skincare is also key. Combining Arctiva with good moisturizing and avoidance of eczema triggers will enhance treatment effectiveness.
Hydrating the Skin
Even when inflammation subsides, eczema leaves skin extremely vulnerable to drying and cracking. Rich emollient creams, ointments and lotions - free of irritants and fragrances - are crucial to restoring protective skin barrier function.
Moisturize multiple times throughout the day, especially soon after bathing when damp skin readily absorbs hydration. Occlusive petroleum jelly products excel for sealing in moisture overnight.
Avoiding Triggers
Common eczema triggers like harsh soaps, scratchy fabrics, temperature swings, foods and stress can still stir up flare ups regardless of using Arctiva. Identify and minimize contact with anything that visibly reddens or itches your skin.
Wear soft, breathable natural fabrics like cotton. Wash laundry without fragrances or dyes. Maintain comfortable sleeping temperatures and humidity levels.
Bathing Best Practices
Daily showers or baths risk stripping away natural oils protecting eczema-prone skin. Limit washing to twice weekly, using lukewarm rather than hot water. Choose gentle cleansers labeled “fragrance free” for sensitive skin types.
Pat skin partially dry after bathing, allowing some moisture to remain on the surface. Immediately apply your preferred hydrating cream or ointment from neck down to trap in that moisture.
Avoid Scratching
Scratching eczema rashes significantly worsens inflammation and skin injury. Keep fingernails closely trimmed to minimize damage if scratching temptations strike. Place hydrocolloid bandages over especially bothersome spots.
Try tapping the itchy area instead of raking nails over it. Cold compresses, antihistamines, distractions and other itch relief tricks can also help resist scratching urges until Arctiva calms those symptoms.
Is Arctiva Right for You?
Arctiva cream represents an exciting, steroid-free path for durable eczema relief. Its twice-daily JAK-inhibiting formula confronts the underlying immune dysfunction perpetuating flares from the inside out.
Clinical trial participants enjoyed major improvements in itching, redness, cracking and scale severity scores. Almost two-thirds rated Arctiva highly acceptable for long-term disease maintenance after just a month of treatment.
Speak to your dermatologist or allergist about adding complementary Arctiva therapy if topical steroids or other existing approaches no longer adequately control your or your teen’s frustrating eczema outbreaks. Taming unruly flare ups requires a multi-pronged effort, but remission is often within reach with today’s expanding medical options.
FAQs
How does the new eczema cream Arctiva work?
Arctiva contains the active drug ruxolitinib, which blocks inflammatory JAK enzyme signals in the body that drive eczema flare ups and skin inflammation.
What are the potential side effects of using Arctiva cream?
Mild temporary reactions like burning, stinging, or redness at the application site may occur initially but resolve quickly. Discontinue use if any severe symptoms or suspected allergic reactions develop.
Should you use moisturizers while using Arctiva for eczema?
Yes, combining Arctiva with gentle, fragrance-free moisturizers is vital for restoring the damaged skin barrier in eczema and preventing further flares. Hydrate skin multiple times per day.
Who should avoid using the new eczema cream Arctiva?
Arctiva should be avoided by pregnant/nursing women, immunosuppressed patients, those with active infections, and anyone allergic to Arctiva's ingredients due to safety concerns.
Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult with a healthcare professional before starting any new treatment regimen.
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