What is Creatine?
Creatine is one of the most popular sports supplements on the market. It is a naturally occurring compound that is found in your body, primarily in your muscles. Creatine plays an important role in providing energy for your muscles during high-intensity activities like weight lifting or sprinting.
The creatine found in supplements is usually creatine monohydrate, which is essentially just creatine with a water molecule attached. When you take a creatine supplement, the creatine gets stored in your muscles and helps provide additional energy by increasing the formation of adenosine triphosphate (ATP).
ATP is the primary energy source for high-intensity, short-duration activities. The more ATP your muscles have access to, the more energy they can generate during exercise. This can lead to better performance and greater training adaptations like increased strength and muscle growth over time.
Benefits of Creatine
Here are some of the main evidence-based benefits of creatine supplementation:
- Increases strength and power output
- Helps you perform more reps with a given weight
- Enhances muscle mass and lean body mass gains from resistance training
- Can improve high-intensity anaerobic capacity
- May help boost sprint performance
- Speeds post-workout muscle recovery and reduces muscle damage from training
The performance and training benefits of creatine make it appealing for athletes engaged in high-intensity sports like weight lifting, hockey, football, wrestling, track & field events, and more.
How Much Creatine Should You Take?
The standard daily dosage recommendation for creatine is about 2-5 grams per day. This is typically split into four separate 1 gram doses taken throughout the day. Some people "load" with 20 grams per day for 5-7 days when first starting creatine to help saturate their muscles faster.
Taking 2-5 grams per day (after the loading phase if you choose to do one) is generally recommended for long-term creatine use. This seems to produce optimal results on muscle creatine stores and performance while minimizing the risk of side effects.
Is 2g of Creatine Enough?
While 2 grams per day is at the lower end of the standard dosage range, research has shown that it can still be an effective dose for increasing muscle creatine and improving exercise performance.
In one study, training individuals took either 2 or 5 grams of creatine monohydrate per day over 42 days. Both groups increased their muscle creatine stores by a similar amount and saw comparable increases in bench press and jump squat performance.
Other research on young women found that just 2 grams of creatine per day in conjunction with resistance training for 10 weeks significantly increased upper and lower body strength compared to a placebo.
Two grams per day may be enough to provide ergogenic benefits for some people, especially among lighter individuals with less total muscle mass. However, people with more muscle mass may need closer to 3-5 grams daily to maximize creatine storage and performance benefits.
Benefits of Higher Doses
While 2 grams is sufficient for many, using a slightly higher dose like 3-5 grams per day can provide additional advantages:
- Maximizes intramuscular creatine stores faster and to a greater extent
- Enhances strength and power output potential
- Greater muscle mass and lean mass gains over time
- May improve anaerobic and high-intensity exercise capacity further
So in summary, getting in 2 grams per day will certainly produce benefits for most people, especially recreational lifters. But athletes looking to maximize performance may see even greater gains topping off at 3-5 grams per day.
When to Take Creatine
In terms of timing, the best time to take creatine is generally anytime throughout the day. Spacing your dosage into 4 equal doses of around 1 gram is a good strategy.
Taking creatine with a quick carb source like fruit juice can help increase absorption. But this is not completely necessary. Taking creatine with water at different times throughout the day works just fine.
One thing to consider is avoiding taking creatine immediately before or during cardio exercise. Since creatine pulls water into your muscle cells, it can potentially cause cramping during endurance activities. Have your final dose at least an hour before any cardio workout.
Pre vs Post Workout
As for taking creatine before or after workouts, either time can work. Taking creatine after training may help deliver additional nutrients for muscle recovery and growth. But taking it before can help provide energy during your workout.
A good pre-workout creatine dose is around 3-5 grams taken 30-60 minutes before training. For post-workout, 3-5 grams in your protein shake is effective.
Splitting your daily dose with half before and half after workouts is another great option to reap the benefits any time of day.
Loading Phase: Is it Necessary?
One popular strategy is to do a "loading phase" when you first start supplementing with creatine. This involves taking very high doses of 20 grams per day for 5-7 days.
In theory, the loading phase helps rapidly increase your intramuscular creatine stores faster to maximize performance benefits. However, research has shown that this may not be necessary.
Studies demonstrate that simply taking the standard dosage of 2-5 grams per day for 28 days raised muscle creatine to the same level as doing a loading phase. The only difference is that it takes a few weeks longer to maximize muscle stores without a loading phase.
For most people, skipping the loading phase and just sticking with a standard dose long-term is the simplest and most efficient approach.
Downsides of Loading
Here are some potential downsides of doing a creatine loading phase:
- Requires taking large amounts of creatine for a week, which some people may not tolerate well gastrointestinally
- Can cause quick initial weight gain, mostly from increased water retention
- May increase risk of side effects like cramping or diarrhea
- Unnecessary if you are looking for gradual improvements over a longer period
Unless you are looking to maximize muscle creatine content and performance gains in just 1-2 weeks, the loading phase is likely an unnecessary hassle.
Creatine Response: Do Genetics Matter?
It turns out that genetics play a major role in determining how well someone responds to creatine supplementation. Research has identified several genetic polymorphisms that can influence creatine uptake and utilization.
People with certain genotypes seem to experience greater increases in muscle creatine content and see greater performance and training adaptations from creatine use.
However, the effect is not completely black and white. Even "non-responders" usually see some benefits from using creatine, just perhaps not to the same magnitude as genetically gifted "high-responders."
In addition, factors like initial muscle creatine levels, muscle fiber composition, and amount/intensity of training also impact individual responses. The more trained your muscles are, the better they'll typically uptake and use additional creatine.
Can Blood Tests Show Responders?
While genetic tests can identify potential responders, blood tests to measure creatinine levels can also provide insight.
Creatinine is a metabolic byproduct of creatine breakdown in your body. If creatinine goes up substantially in your blood after supplementing with creatine, it generally indicates your body is absorbing and utilizing the additional creatine.
However, blood creatinine can be influenced by other factors like diet and hydration. So genetic polymorphism analysis and muscle biopsies provide the most definitive way to identify responders.
Side Effects and Safety
Creatine is widely considered safe for most adults when taken at recommended dosages. However, there are some potential side effects and considerations:
- Weight gain - Creatine typically causes quick initial weight gain due to increased water retained in the muscles. This is normal and levels out after a few weeks.
- Cramping - Due to fluid shifts, some users report muscle cramping when supplementing with creatine, especially during endurance exercise.
- Digestive issues - Creatine can cause diarrhea, nausea, and stomach discomfort in some individuals, especially at higher doses.
- Dehydration - Increased water drawn into the muscle means water needs increase. Be sure to stay properly hydrated.
High doses for prolonged periods could potentially damage the kidneys in those predisposed to kidney issues. But standard creatine doses have not been shown to be harmful to kidney function in healthy individuals.
Due to limited research, creatine is not recommended for those under 18 years old. Pregnant or breastfeeding women should also avoid creatine out of caution.
Cycling Off Creatine
Cycling on and off creatine instead of taking it continuously can help minimize any potential side effects. A typical cycle is 8-12 weeks on creatine and then 4 weeks off.
However, research has not clearly demonstrated that cycling is necessary. With standard long-term doses, muscle creatine levels remain stable and side effects minimal for most people.
Creatine FAQ
Is creatine a steroid?
No, creatine is not a steroid. Creatine is produced naturally in the body to provide energy for cells, while anabolic steroids are synthetic compounds that mimic testosterone.
Is creatine safe for kids and teens?
Creatine is not recommended for those under 18. Teens should avoid creatine due to limited research on the effects in this population.
When is the best time to take creatine?
Creatine can be taken any time of day. Taking smaller doses of 1-2 grams spread throughout the day may be optimal for absorption. Take creatine at least 1 hour before cardio exercise to avoid potential cramping.
Do you need to cycle creatine?
Cycling creatine by taking it for 8-12 weeks and then off for 4 weeks is not necessary but can help minimize side effects. With standard recommended doses, creatine does not need to be cycled for most people.
Does creatine cause hair loss or baldness?
There is no evidence creatine causes hair loss or male pattern baldness. However, creatine can raise DHT levels, which for those predisposed to hair loss could potentially accelerate it.
Can creatine cause acne?
Creatine itself does not directly cause acne, but it draws water into muscle cells. This can potentially lower water content in the skin and exacerbate dryness and acne.
Is creatine bad for your kidneys?
In healthy individuals, standard creatine doses have not been shown to adversely affect kidney function. But high doses could potentially be harmful for those with pre-existing kidney conditions.
The Bottom Line
While 2 grams per day is enough to increase muscle creatine stores and performance for most people, 3-5 grams daily provides maximum benefits.
Taking 2-5 grams per day long-term, without an initial loading phase, is the simplest and most effective approach for the majority of people looking to improve exercise performance and training adaptations.
Remember to split your dosage throughout the day and stay well-hydrated when supplementing with creatine. Be aware of any potential side effects and consider cycling on and off periodically.
With the proper dosage and usage, creatine can provide significant strength, muscle, and performance benefits for athletes and recreational lifters alike.
FAQs
What are the benefits of creatine?
Creatine has been shown to increase muscle strength, power, and endurance. It can help you perform more reps with a given weight and enhance lean muscle mass gains from training.
When should I take creatine?
You can take creatine anytime throughout the day. Taking smaller doses of 1-2 grams spread out is optimal. Avoid taking creatine right before cardio exercise to prevent cramping.
Do I need to do a loading phase?
A loading phase of 20 grams per day for 5-7 days is not necessary. You can saturate your muscles by taking 2-5 grams per day for 4 weeks without loading.
Can creatine cause bloating?
Creatine pulls water into your muscles, so temporary water weight gain and bloating can occur initially. This subsides within 1-2 weeks for most people as your body adjusts.
Is creatine safe long-term?
Yes, creatine is safe for long-term use at recommended dosages of 2-5 grams per day. There is no evidence it causes harm to kidneys or other organs with standard supplemental doses.
Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult with a healthcare professional before starting any new treatment regimen.
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