Understanding Basal Cell Carcinoma Progression When Left Untreated
Basal cell carcinoma (BCC) is the most common type of skin cancer. Over 4 million cases are diagnosed in the United States each year. BCCs develop in the basal cells, which are the deepest layer of the epidermis (outer skin layer).
BCC often shows up as open sores or reddish patches on sun-exposed areas like the face, neck and arms. Fortunately, BCC rarely spreads to other parts of the body when diagnosed and removed early.
What Happens When Basal Cell Carcinoma Goes Untreated?
The initial changes of a developing BCC are microscopic. Over months to years, the lesions grow progressively larger, destroying healthy skin cells. Though BCC spreads slowly, leaving the cancer untreated for longer periods allows more extensive skin damage and larger lesions.
How BCCs Grow and Advance
As BCC cells multiply, they release enzymes that damage surrounding skin. This erosion creates an open wound that keeps expanding outward and downward as the cancer cells continue invading healthy tissue.
Initially, the immune system attempts to repair the eroded skin. But the high turnover rate of malignant BCC cells overwhelms this regeneration response. With time, lesions grow wider and burrow deeper into layers beneath the skin.
What to Expect with BCC After 2 Years Untreated
When basal cell carcinomas are left alone for 2 years or more, the continuing destruction of healthy skin cells, blood vessels and other tissues leads to some common and concerning changes:
Expanded Lesion Size
The longer BCC goes untreated, the larger the lesion tends to grow. Over 2 years, an untreated lesion can extend well beyond 1-2 centimeters in diameter across the skin surface. Invasion deeper underneath the upper skin layers also progresses.
Increased Nerve Damage
As the advancing BCC erodes down past the epidermis into the dermis, sensory nerves become implicated. Nerve damage causes numbness in skin areas around or within the lesion site.
Nerves control sensation and function for facial muscles and various body areas. Impacting these through BCC growth can lead to loss of touch perception, motor difficulties like weakened facial movements, pain or uncontrollable twitching.
Scarring and Disfigurement
Untreated BCCs destroy skin architecture leading to significant scarring. After several years, the normal contours of the face or body part affected become increasingly warped from sizable lesions and tissue loss.
Ongoing erosion into cartilage of the ears or nose can cause complete or partial loss of these features. Similarly, neglected growths on the lips may penetrate completely through if not addressed promptly.
Risks of Advanced Basal Cell Carcinomas
Though this skin cancer advances slowly compared to other types like melanoma, the risks of leaving BCC untreated long-term include:
Metastasis
When basal cell carcinomas extend deeply into facial bones or around nerve areas, the chance of cancer cells spreading (metastasizing) to distant sites like the brain, spine or lungs goes up.
Metastatic BCC remains rare, occurring only in an estimated 0.1% of cases. But neglected tumors present for 10 years or longer carry higher odds of metastasizing and worse prognosis.
Recurrence After Treatment
With early diagnosis and prompt removal, BCC cure rates exceed 95%. However, untreated lesions penetrating down to bone have only a 60% non-recurrence rate even after extensive treatment like surgery and radiation.
Major Functional Impairment
If neglected basocellular lesions erode into sinus cavities, tear ducts or other critical head/neck structures, loss of normal sensation or function may become permanent. Impacting cranial nerves through tumor invasion also causes substantial morbidity.
Emotional Distress
Facial disfigurement, reduced quality of life going out in public, inability to move face muscles for expression, and chronic pain require substantial emotional adjustment and support.
Seeking Early BCC Evaluation
Catching BCC skin lesions when they first arise or at least within several months leads to simpler, more effective treatment options with excellent cure rates and cosmetic results.
See your dermatologist promptly if you notice any unusual skin changes, sores, bumps or reddish patches that dont go away, particularly on the head, neck and upper body.
Look for BCC warning signs like:
- Pearly, waxy bump on face/ears/neck
- Flat, scaly, crusty reddish patch
- Open sore that bleeds, oozes or crusts over
- Raised reddish growth with raised borders
- Scar-like indentation on skin
Catching concerning skin changes early not only improves prognosis but also reduces treatment intensity needed for the best outcome. Dont wait to bring worrisome spots or growths to your doctors attention.
FAQs
How fast does an untreated basal cell carcinoma grow?
BCCs left alone tend to grow progressively larger over months to years. After 2 years untreated, lesions often extend more than 1-2 centimeters wide and invade deeper under the skin.
What happens if basal cell carcinoma is not treated?
Untreated BCC leads to expanding destruction of healthy skin cells, blood vessels and tissues. This results in wider lesions, nerve injury, major scarring/disfigurement and higher risk of metastasis or recurrence.
Can an untreated basal cell carcinoma kill you?
Metastatic basal cell carcinoma is rare but possible when large neglected tumors extend into facial bones or nerves. Metastatic BCC invading vital organs can be life threatening though non-metastatic types are seldom fatal.
Does basal cell carcinoma hurt if left untreated?
Most smaller BCCs don't hurt initially. But larger, advancing lesions often become painful from nerve damage in surrounding skin. Ongoing erosion into cartilage or bone also leads to substantial pain.
What is the most effective treatment for an advanced basal cell carcinoma?
Larger BCCs require more extensive treatment like surgical excision, tissue grafting or Mohs surgery. Radiation or targeted drug therapy may supplement surgery for recurrent lesions or those reaching nerve areas or bone.
Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult with a healthcare professional before starting any new treatment regimen.
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